Neuro Forum Multiple serotonergic paths to antidepressant efficacy
نویسنده
چکیده
Lutz P.-E. Multiple serotonergic paths to antidepressant efficacy. J Neurophysiol 109: 2245–2249, 2013. First published January 23, 2013; doi:10.1152/jn.01093.2012.—Depression is a leading cause of disability worldwide. Brain mechanisms underlying the clinical antidepressant efficacy of selective serotonin reuptake inhibitors (SSRI), currently the first-line treatment, remain poorly understood. Recent animal studies have implicated multiple serotonin receptor subtypes in SSRI response, opening new therapeutic perspectives.
منابع مشابه
Multiple serotonergic paths to antidepressant efficacy.
Depression is a leading cause of disability worldwide. Brain mechanisms underlying the clinical antidepressant efficacy of selective serotonin reuptake inhibitors (SSRI), currently the first-line treatment, remain poorly understood. Recent animal studies have implicated multiple serotonin receptor subtypes in SSRI response, opening new therapeutic perspectives.
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